Prediction of membranoproliferative glomerulonephritis in nephrotic children from clinicolaboratory data.

Prediction of the histology of MPGN was performed without doing a renal biopsy by a univariate and multivariate analysis of three histological groups in nephrotic children: membranoproliferative glomerulonephritis (MPGN, N=13), proliferative glomerulonephritis (PGN, N=11) and minimal change nephrotic syndrome (MCNS, N=10). If the Y value of the following equation exceeded 0.41, the probability of MPGN was very high with a misdiscrimination rate of 4.8 %. A Y value less than 0.41 eliminated the possibility of MPGN.